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stereo seq whole mouse brain dataset  (Complete Genomics Inc)


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    Complete Genomics Inc stereo seq whole mouse brain dataset
    Performance of STCS on <t>high-resolution</t> <t>Stereo-seq</t> mouse brain data. A) Tissue images and segmentations. Left: original H&E image; Center: nuclei segmentation mask; Right: Single-cell Segmented slide by STCS (colored by cell class, defined as higher-level groupings of CellTypist-predicted cell types. B) Spatial continuity metrics. Left: Cell-class coherence across neighborhood size. computed as the proportion of spatially nearest neighbors sharing the same cell-class label at each neighborhood size. Higher values indicate greater spatial consistency of cell-class assignments within local tissue contexts. Middle: CHAOS scores computed at the Leiden cluster level. Right: CHAOS scores computed at the cell-class level. Lower CHAOS scores indicate better spatial organization. The center line represents the median CHAOS score and the box spans the interquartile range. The annotated text are µ ± σ . C) Gene Level metrics. Left: Cell-class label-transfer accuracy to a scRNA-seq reference across varying numbers of highly variable genes (HVGs), assessing how reliably reconstructed spatial cells recover reference-defined transcriptional identities and the robustness of predictions based on different selected features. Right: Distribution of gene-expression cosine similarity between reconstructed cells and scRNA-seq reference profiles across cell classes, quantifying transcriptomic agreement. Cosine similarity was computed between each reconstructed cell’s expression profile and the mean expression profile of its assigned cell class in the scRNA-seq reference. Center lines indicate medians and boxes span the interquartile range. The annotated text are µ ± σ . D) Cell-type composition accuracy. Left: Cell-type richness between methods and a single-cell reference data. Right: Absolute error in estimated cellclass proportions compared to the reference. Lower values indicate closer agreement with the cellular composition of the reference data. The annotated text are µ ± σ and center lines indicate median.
    Stereo Seq Whole Mouse Brain Dataset, supplied by Complete Genomics Inc, used in various techniques. Bioz Stars score: 97/100, based on 339 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/stereo seq whole mouse brain dataset/product/Complete Genomics Inc
    Average 97 stars, based on 339 article reviews
    stereo seq whole mouse brain dataset - by Bioz Stars, 2026-04
    97/100 stars

    Images

    1) Product Images from "STCS: A Platform-Agnostic Framework for Cell-Level Reconstruction in Sequencing-Based Spatial Transcriptomics"

    Article Title: STCS: A Platform-Agnostic Framework for Cell-Level Reconstruction in Sequencing-Based Spatial Transcriptomics

    Journal: bioRxiv

    doi: 10.64898/2026.02.26.708370

    Performance of STCS on high-resolution Stereo-seq mouse brain data. A) Tissue images and segmentations. Left: original H&E image; Center: nuclei segmentation mask; Right: Single-cell Segmented slide by STCS (colored by cell class, defined as higher-level groupings of CellTypist-predicted cell types. B) Spatial continuity metrics. Left: Cell-class coherence across neighborhood size. computed as the proportion of spatially nearest neighbors sharing the same cell-class label at each neighborhood size. Higher values indicate greater spatial consistency of cell-class assignments within local tissue contexts. Middle: CHAOS scores computed at the Leiden cluster level. Right: CHAOS scores computed at the cell-class level. Lower CHAOS scores indicate better spatial organization. The center line represents the median CHAOS score and the box spans the interquartile range. The annotated text are µ ± σ . C) Gene Level metrics. Left: Cell-class label-transfer accuracy to a scRNA-seq reference across varying numbers of highly variable genes (HVGs), assessing how reliably reconstructed spatial cells recover reference-defined transcriptional identities and the robustness of predictions based on different selected features. Right: Distribution of gene-expression cosine similarity between reconstructed cells and scRNA-seq reference profiles across cell classes, quantifying transcriptomic agreement. Cosine similarity was computed between each reconstructed cell’s expression profile and the mean expression profile of its assigned cell class in the scRNA-seq reference. Center lines indicate medians and boxes span the interquartile range. The annotated text are µ ± σ . D) Cell-type composition accuracy. Left: Cell-type richness between methods and a single-cell reference data. Right: Absolute error in estimated cellclass proportions compared to the reference. Lower values indicate closer agreement with the cellular composition of the reference data. The annotated text are µ ± σ and center lines indicate median.
    Figure Legend Snippet: Performance of STCS on high-resolution Stereo-seq mouse brain data. A) Tissue images and segmentations. Left: original H&E image; Center: nuclei segmentation mask; Right: Single-cell Segmented slide by STCS (colored by cell class, defined as higher-level groupings of CellTypist-predicted cell types. B) Spatial continuity metrics. Left: Cell-class coherence across neighborhood size. computed as the proportion of spatially nearest neighbors sharing the same cell-class label at each neighborhood size. Higher values indicate greater spatial consistency of cell-class assignments within local tissue contexts. Middle: CHAOS scores computed at the Leiden cluster level. Right: CHAOS scores computed at the cell-class level. Lower CHAOS scores indicate better spatial organization. The center line represents the median CHAOS score and the box spans the interquartile range. The annotated text are µ ± σ . C) Gene Level metrics. Left: Cell-class label-transfer accuracy to a scRNA-seq reference across varying numbers of highly variable genes (HVGs), assessing how reliably reconstructed spatial cells recover reference-defined transcriptional identities and the robustness of predictions based on different selected features. Right: Distribution of gene-expression cosine similarity between reconstructed cells and scRNA-seq reference profiles across cell classes, quantifying transcriptomic agreement. Cosine similarity was computed between each reconstructed cell’s expression profile and the mean expression profile of its assigned cell class in the scRNA-seq reference. Center lines indicate medians and boxes span the interquartile range. The annotated text are µ ± σ . D) Cell-type composition accuracy. Left: Cell-type richness between methods and a single-cell reference data. Right: Absolute error in estimated cellclass proportions compared to the reference. Lower values indicate closer agreement with the cellular composition of the reference data. The annotated text are µ ± σ and center lines indicate median.

    Techniques Used: Single Cell, Gene Expression, Expressing



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    stereo seq whole mouse brain dataset  (Complete Genomics Inc)
    97
    Complete Genomics Inc stereo seq whole mouse brain dataset
    Performance of STCS on <t>high-resolution</t> <t>Stereo-seq</t> mouse brain data. A) Tissue images and segmentations. Left: original H&E image; Center: nuclei segmentation mask; Right: Single-cell Segmented slide by STCS (colored by cell class, defined as higher-level groupings of CellTypist-predicted cell types. B) Spatial continuity metrics. Left: Cell-class coherence across neighborhood size. computed as the proportion of spatially nearest neighbors sharing the same cell-class label at each neighborhood size. Higher values indicate greater spatial consistency of cell-class assignments within local tissue contexts. Middle: CHAOS scores computed at the Leiden cluster level. Right: CHAOS scores computed at the cell-class level. Lower CHAOS scores indicate better spatial organization. The center line represents the median CHAOS score and the box spans the interquartile range. The annotated text are µ ± σ . C) Gene Level metrics. Left: Cell-class label-transfer accuracy to a scRNA-seq reference across varying numbers of highly variable genes (HVGs), assessing how reliably reconstructed spatial cells recover reference-defined transcriptional identities and the robustness of predictions based on different selected features. Right: Distribution of gene-expression cosine similarity between reconstructed cells and scRNA-seq reference profiles across cell classes, quantifying transcriptomic agreement. Cosine similarity was computed between each reconstructed cell’s expression profile and the mean expression profile of its assigned cell class in the scRNA-seq reference. Center lines indicate medians and boxes span the interquartile range. The annotated text are µ ± σ . D) Cell-type composition accuracy. Left: Cell-type richness between methods and a single-cell reference data. Right: Absolute error in estimated cellclass proportions compared to the reference. Lower values indicate closer agreement with the cellular composition of the reference data. The annotated text are µ ± σ and center lines indicate median.
    Stereo Seq Whole Mouse Brain Dataset, supplied by Complete Genomics Inc, used in various techniques. Bioz Stars score: 97/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/stereo seq whole mouse brain dataset/product/Complete Genomics Inc
    Average 97 stars, based on 1 article reviews
    stereo seq whole mouse brain dataset - by Bioz Stars, 2026-04
    97/100 stars
    		  Buy from Supplier

    Image Search Results


    Performance of STCS on high-resolution Stereo-seq mouse brain data. A) Tissue images and segmentations. Left: original H&E image; Center: nuclei segmentation mask; Right: Single-cell Segmented slide by STCS (colored by cell class, defined as higher-level groupings of CellTypist-predicted cell types. B) Spatial continuity metrics. Left: Cell-class coherence across neighborhood size. computed as the proportion of spatially nearest neighbors sharing the same cell-class label at each neighborhood size. Higher values indicate greater spatial consistency of cell-class assignments within local tissue contexts. Middle: CHAOS scores computed at the Leiden cluster level. Right: CHAOS scores computed at the cell-class level. Lower CHAOS scores indicate better spatial organization. The center line represents the median CHAOS score and the box spans the interquartile range. The annotated text are µ ± σ . C) Gene Level metrics. Left: Cell-class label-transfer accuracy to a scRNA-seq reference across varying numbers of highly variable genes (HVGs), assessing how reliably reconstructed spatial cells recover reference-defined transcriptional identities and the robustness of predictions based on different selected features. Right: Distribution of gene-expression cosine similarity between reconstructed cells and scRNA-seq reference profiles across cell classes, quantifying transcriptomic agreement. Cosine similarity was computed between each reconstructed cell’s expression profile and the mean expression profile of its assigned cell class in the scRNA-seq reference. Center lines indicate medians and boxes span the interquartile range. The annotated text are µ ± σ . D) Cell-type composition accuracy. Left: Cell-type richness between methods and a single-cell reference data. Right: Absolute error in estimated cellclass proportions compared to the reference. Lower values indicate closer agreement with the cellular composition of the reference data. The annotated text are µ ± σ and center lines indicate median.

    Journal: bioRxiv

    Article Title: STCS: A Platform-Agnostic Framework for Cell-Level Reconstruction in Sequencing-Based Spatial Transcriptomics

    doi: 10.64898/2026.02.26.708370

    Figure Lengend Snippet: Performance of STCS on high-resolution Stereo-seq mouse brain data. A) Tissue images and segmentations. Left: original H&E image; Center: nuclei segmentation mask; Right: Single-cell Segmented slide by STCS (colored by cell class, defined as higher-level groupings of CellTypist-predicted cell types. B) Spatial continuity metrics. Left: Cell-class coherence across neighborhood size. computed as the proportion of spatially nearest neighbors sharing the same cell-class label at each neighborhood size. Higher values indicate greater spatial consistency of cell-class assignments within local tissue contexts. Middle: CHAOS scores computed at the Leiden cluster level. Right: CHAOS scores computed at the cell-class level. Lower CHAOS scores indicate better spatial organization. The center line represents the median CHAOS score and the box spans the interquartile range. The annotated text are µ ± σ . C) Gene Level metrics. Left: Cell-class label-transfer accuracy to a scRNA-seq reference across varying numbers of highly variable genes (HVGs), assessing how reliably reconstructed spatial cells recover reference-defined transcriptional identities and the robustness of predictions based on different selected features. Right: Distribution of gene-expression cosine similarity between reconstructed cells and scRNA-seq reference profiles across cell classes, quantifying transcriptomic agreement. Cosine similarity was computed between each reconstructed cell’s expression profile and the mean expression profile of its assigned cell class in the scRNA-seq reference. Center lines indicate medians and boxes span the interquartile range. The annotated text are µ ± σ . D) Cell-type composition accuracy. Left: Cell-type richness between methods and a single-cell reference data. Right: Absolute error in estimated cellclass proportions compared to the reference. Lower values indicate closer agreement with the cellular composition of the reference data. The annotated text are µ ± σ and center lines indicate median.

    Article Snippet: The Stereo-seq whole mouse brain dataset is available from STOmics ( https://en.stomics.tech/col1241/index.html ).

    Techniques: Single Cell, Gene Expression, Expressing